Healthy cognitive function

Supports processes involved in
learning, memory and calm
focus and helps maintain
cognitive health 1-4

Working memory

Improves memory and learning
retention helping you to
process and remember
information 1-4

Concentration & focus

Helps improve attention
span and support mental clarity.1,4

Central Drug
Research Institute

A product of CSIR | CDRI

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Brahmi (Bacopa monnieri - CDRI 08)

Memory and concentration support

Bacopa Monnieri, commonly known as Brahmi or Bacopa used in Mind Wise, is a medicinal herb, used for generations in Ayurvedic medicine for supporting memory, concentration and learning capacity.

In Mind Wise, a specific standardised extract of Bacopa Monnieri, known as CDRI 08, is used. Mind Wise with CDRI 08 has been extensively researched for over 40 years* to support cognitive health.1-8

Healthy cognitive function

Supports processes involved in learning, memory and calm focus and helps maintain cognitive health 1-4

Working memory

Supports processes involved in learning, memory and calm focus and helps maintain cognitive health 1-4

Concentration & Focus

Supports processes involved in learning, memory and calm focus and helps maintain cognitive health 1-4

Bacopa monnieri in history

Bacopa monnieri, also known as Brahmi, is a small creeping herb found throughout the Indian subcontinent.

More about Brahmi in traditional medicine

It has been used in Ayurvedic medicine for almost 3000 years. Throughout this time, it has been associated with a variety of health benefits including heightened learning capacity, promoting memory and concentration, as a nerve tonic and to support cardiovascular health.

It is the memory and learning effects of Bacopa that have attracted the most attention in the last few decades and, in doing so, have become the subject of much clinical research

The specific extract used in Mind Wise: CDRI 08

CDRI 08 is the specific Bacopa monnieri extract used by Life Essence in Mind Wise. It was first researched in the 1970s by the Indian government’s Central Drug Research Institute and has been the subject of research for more than 40 years* to support its benefits for cognitive health.More about CDRI 08The memory-supporting effect of CDRI 08 is based on numerous clinical trials. Results from these clinical trials suggest that CDRI 08 in Mind Wise helps to:1-6·

Maintain healthy cognitive function·
Improve working memory·
Assist in learning retention·
Assist with concentration and focus as well as keeping to task and maintaining attention span·
Can be beneficial during times of stress or mild anxiety

CDRI 08 in Mind Wise: Clinical trials

The specific CDRI 08 extract of Bacopa monnieri has been researched in multiple randomised controlled trials demonstrating that it can help improve cognitive function and is well tolerated at the recommended dose. 1-6 The table below covers a selection of key clinical studies on CDRI 08.

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SIGNIFICANT IMPROVEMENT
vs. placebo for:
speed of visual information processing
learning rate
memory consolidation
forgetting rate
mild state of anxiety

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.
Read More
SIGNIFICANT IMPROVEMENT
vs. placebo for:

mental control logical memory paired associated learning

Raghav S, et al. Indian J Psychiatry 2006;48(4):238-242.

Read More
SIGNIFICANT IMPROVEMENT
vs. placebo for:

retention of new information

Roodenrys S, et al. Neuropsychopharmacology 2002;27(2):279-281.
Read More
POSITIVE EFFECT
vs. placebo for:

acute cognitive function mood stress

Benson S, et al. Phytother Res 2014;28(4):551-559.

Read More
SIGNIFICANT IMPROVEMENT
vs. placebo for:

working memory mistakes in visual information processing

Stough C, et al. Phytother Res 2008;22(12):1629-634.
Read More
POSITIVE EFFECT
vs. placebo for:

improved cognitive performance, including:
information processing, decision making time, and attention or freedom from distractibility

Downey LA, et al. Phytother Res 2012;27(9):1407-1413..

1. The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

2. Chronic effects of Brahmi (Bacopa monnieri) on human memory

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

3. Examining the nootropic effects of a special extract of Bacopa monniera on human cognitive functioning: 90 day double-blind placebo-controlled randomized trial

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

4. Randomized controlled trial of standardized Bacopa monniera extract in age-associated memory impairment

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

5. An acute, double-blind, placebo-controlled crossover study of 320 mg and 640 mg doses of a special extract of Bacopa monnieri (CDRI 08) on sustained cognitive performance

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

6. An acute, double-blind, placebo-controlled crossover study of 320 mg and 640 mg doses of a special extract of Bacopa monnieri (CDRI 08) on sustained cognitive performance

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

7. A Randomized Controlled Trial Investigating the Effects of a Special Extract of Bacopa monnieri (CDRI 08) on Hyperactivity and Inattention in Male Children and Adolescents: BACHI Study Protocol (ANZCTRN12612000827831)

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

8. Randomized controlled trial of standardized Bacopa monniera extract in age-associated memory impairment

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

9. Brain Enhancing Ingredients from Āyurvedic Medicine: Quintessential Example of Bacopa monniera, a Narrative Review

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

10. Bacopa monnieri as an Antioxidant Therapy to Reduce Oxidative Stress in the Aging Brain

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

11. Antioxidant activity of Bacopa monniera in rat frontal cortex, striatum and hippocampus

Bhattacharya SK et al Phytother. Res. 2000;14: 174–179

12. Bacopa monnieri Extract (CDRI-08) Modulates the NMDA Receptor Subunits and nNOS-Apoptosis Axis in Cerebellum of Hepatic Encephalopathy Rats

Mondal P et al. Evid Based Complementary Altern Med 2015; Article ID 535013.

13. A comparative study in rodents of standardized extracts of Bacopa monniera and Ginkgo biloba: anticholinesterase and cognitive enhancing activities

Das et al. Pharmacol Biochem Behav 2002; 73 (4):893-900

14. Rajan et al. Neurochem Res 2011; 36 (11):2136-44 [S14-0165].

15. Adaptogenic effect of Bacopa monniera (Brahmi)

Rai D, et al. Pharmacol Biochem Behav 2003;75:823-830.

CDRI 08: A Summary

Consistent quality
Through our rigorous processes, quality controls and extensive testing we help ensure that every batch of Mind Wise can provide the desired health outcomes demonstrated by clinical studies.

40 years of research

Beginning in 1974* by the Central Drug Research Institute (CDRI) in India and more recently in Australia.

8 Clinical trials

Mind Wise clinical studies support its role in improving cognitive function1-8

Recommended worldwide

to support cognitive health, memory, concentration and learning retention.

Healthy cognitive function

Working memory

Concentration & focus

Central Drug
Research Institute

Brahmi (Bacopa monnieri - CDRI 08)

Memory and concentration support

Healthy cognitive function

Supports processes involved in learning, memory and calm focus and helps maintain cognitive health 1-4

Working memory

Supports processes involved in learning, memory and calm focus and helps maintain cognitive health 1-4

Concentration & Focus

Supports processes involved in learning, memory and calm focus and helps maintain cognitive health 1-4

Bacopa monnieri in history

The specific extract used in Mind Wise: CDRI 08

CDRI 08 in Mind Wise: Clinical trials

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

Bhattacharya SK et al Phytother. Res. 2000;14: 174–179

Mondal P et al. Evid Based Complementary Altern Med 2015; Article ID 535013.

Das et al. Pharmacol Biochem Behav 2002; 73 (4):893-900

Rai D, et al. Pharmacol Biochem Behav 2003;75:823-830.

CDRI 08: A Summary

Consistent quality
Through our rigorous processes, quality controls and extensive testing we help ensure that every batch of Mind Wise can provide the desired health outcomes demonstrated by clinical studies.

40 years of research

8 Clinical trials

Recommended worldwide

Central Drug
Research Institute
A Product of CSIR | CDRI

Customer Service

Healthy cognitive function

Working memory

Concentration & focus

Central Drug Research Institute

Brahmi (Bacopa monnieri - CDRI 08)

Memory and concentration support

Healthy cognitive function

Supports processes involved in learning, memory and calm focus and helps maintain cognitive health 1-4

Working memory

Supports processes involved in learning, memory and calm focus and helps maintain cognitive health 1-4

Concentration & Focus

Supports processes involved in learning, memory and calm focus and helps maintain cognitive health 1-4

Bacopa monnieri in history

CDRI 08 in Mind Wise: Clinical trials

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

Bhattacharya SK et al Phytother. Res. 2000;14: 174–179

Mondal P et al. Evid Based Complementary Altern Med 2015; Article ID 535013.

Das et al. Pharmacol Biochem Behav 2002; 73 (4):893-900

Rai D, et al. Pharmacol Biochem Behav 2003;75:823-830.

CDRI 08: A Summary

Consistent quality Through our rigorous processes, quality controls and extensive testing we help ensure that every batch of Mind Wise can provide the desired health outcomes demonstrated by clinical studies.

40 years of research

8 Clinical trials

Recommended worldwide

Central Drug Research Institute A Product of CSIR | CDRI

Central Drug
Research Institute

Consistent quality
Through our rigorous processes, quality controls and extensive testing we help ensure that every batch of Mind Wise can provide the desired health outcomes demonstrated by clinical studies.

Central Drug
Research Institute
A Product of CSIR | CDRI